List Corrected on March
9, 2001
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The Office of Environmental Health Hazard Assessment
(OEHHA) of the California Environmental Protection Agency is adding
thirteen chemicals to the list of chemicals known to the State
to cause cancer or reproductive toxicity for purposes of the Safe
Drinking Water and Toxic Enforcement Act of 1986 (Proposition
65). The chemicals are listed effective February 27, 2001.
Ethoprop, indium phosphide, lynestrenol, norethynodrel, and propachlor
are listed pursuant to an administrative listing mechanism provided
under Proposition 65, based upon a formal identification by an
authoritative body that the chemicals cause cancer. Regulations
governing the listing of chemicals under the "authoritative
bodies" mechanism are published in Title 22, California Code
of Regulations, Section 12306 (22
CCR 12306).
Amantadine hydrochloride, diazoxide, dichlorphenamide,
diltiazem hydrochloride, filgrastim, and trientine hydrochloride
are listed as chemicals known to the State to cause developmental
toxicity. Ribavirin is listed as a chemical known to the State
to cause male reproductive toxicity and rifampin is listed as
a chemical known to the State to cause developmental and female
reproductive toxicity. The listing of these chemicals is based
on a formal requirement by a state or federal agency that the
chemicals be identified or labeled as causing cancer or reproductive
toxicity pursuant to an administrative listing mechanism provided
under Proposition 65. Regulations governing the listing of chemicals
under the "formally required to be labeled or identified"
mechanism are published in Title 22, California Code of Regulations,
Section 12902 (22 CCR 12902).
The reader is directed to the Notice of Intent to
List Chemicals published in the December
29, 2000 issue of the California Regulatory Notice Register
(Register 00, No. 52-Z) for the supporting documentation for these
chemicals, which OEHHA relied upon in making its determination
that the criteria for administrative listing had been satisfied.
A complete, updated chemical list is published elsewhere
in this issue of the California Regulatory Notice Register.
The thirteen chemicals listed, effective February
27, 2001, and the mechanism under which each is listed, are shown
below:
Chemicals Known to the State to Cause Cancer:
| Chemical |
CAS No. |
Listing Mechanism1 |
|
Ethoprop
Indium phosphide
Lynestrenol
Norethynodrel
Propachlor
|
13194-48-4
22398-80-7
52-76-6
68-23-5
1918-16-7
|
AB
AB
AB
AB
AB
|
Chemicals Known to the State to Cause Reproductive
Toxicity:
| Chemical |
CAS No. |
Endpoint |
Listing Mechanism1
|
| Amantadine hydrochloride |
665-66-7 |
Developmental toxicity |
FR
|
| Diazoxide |
364-98-7 |
Developmental toxicity |
FR
|
| Dichlorphenamide |
120-97-8 |
Developmental toxicity |
FR |
| Diltiazem hydrochloride |
42399-41-7 |
Developmental toxicity |
FR |
| Filgrastim |
121181-53-1 |
Developmental toxicity |
FR |
| Ribavirin* |
36791-04-5 |
Male reproductive toxicity |
FR |
| Rifampin |
13292-46-1 |
Developmental toxicity, Female
reproductive toxicity |
FR |
|
Trientine hydrochloride
|
38260-01-4
|
Developmental toxicity
|
FR
|
*Ribavirin was added to the list of chemicals known
to cause reproductive toxicity on the basis of a developmental
toxicity endpoint on April 1, 1990.
1Listing mechanism:
AB - "authoritative bodies" mechanism
(22 CCR 12306)
FR - "formally required to be labeled or identified"
mechanism (22 CCR 12902)
Download the February 23,
2001 Proposition 65 List:
View the February 23, 2001 Proposition 65 List.
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