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The Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition
65) provides two mechanisms for administratively listing chemicals
which are known to the State to cause reproductive toxicity or cancer
(Health and Safety Code Section 25249.8(b)). One such mechanism
involves the listing of chemicals that a body, considered to be
authoritative by the state's qualified experts, formally identifies
as causing cancer or reproductive toxicity. As the lead agency for
the implementation of Proposition 65, the Office of Environmental
Health Hazard Assessment (OEHHA) of the California Environmental
Protection Agency reviews candidates for listing pursuant to this
administrative mechanism as provided in Health and Safety Code Section
25249.8(b) and Title 22, California Code of Regulations, Section
12306 (22 CCR Section 12306).
The U.S. Environmental Protection Agency (U.S. EPA), an authoritative
body for purposes of Proposition 65 (22 CCR Section 12306(l)), identifies
chemicals as causing developmental or reproductive toxicity in implementing
its Toxic Release Inventory (TRI) program (i.e., Section 313 of
the Emergency Planning and Community Right-to-Know Act of 1986 (EPCRA)).
On this basis the U.S. EPA, in 1994, added a number of chemicals
to the TRI list and published its inclusions to the list in the
Federal Register (59:1788-1859, 1994 and 59:61432-61485, 1994).
OEHHA has reviewed the bases for these TRI chemical additions in
the context of the regulatory criteria governing Proposition 65
listing via the authoritative bodies mechanism (22 CCR Section 12306).
OEHHA determined for several TRI chemicals that the 22 CCR Section
12306 regulatory criteria were met and has placed these chemicals
on the Proposition 65 list of chemicals known to cause reproductive
toxicity. A number of the TRI chemicals were found not to meet the
22 CCR Section 12306 criteria and have been removed from listing
consideration at this time. As described below, OEHHA has determined
that these same regulatory criteria have not been met for diuron.
Diuron was added by U.S. EPA in 1994 to the TRI list on the basis
of developmental toxicity.
In accordance with 22 CCR Section 12306(i), the chemical will be
referred to the Developmental and Reproductive Toxicant (DART) Identification
Committee of the OEHHA Science Advisory Board because the determination
was made subsequent to the issuance of a notice of intent to list
(CRNR, May 21, 1999, Register 99, No. 21-Z). Therefore, at a future
meeting, the DART Identification Committee will opine whether "the
chemical has been clearly shown through scientifically valid testing
according to generally accepted principles" to cause reproductive
toxicity.
TRI chemical not meeting the scientific criteria (22 CCR Section
12306(g)) for authoritative bodies listing as causing reproductive
toxicity under Proposition 65.
| Chemical |
CAS No. |
| Diuron |
330-54-1 |
A document providing more detail on the basis for this determination
can be obtained from OEHHA's Proposition 65 Implementation Office
at the address and telephone number indicated below, or from the
OEHHA Home Page at: http://www.oehha.ca.gov/ . Questions regarding
this notice should be directed to:
Ms. Cynthia
Oshita
Office of Environmental Health Hazard Assessment
Street Address: 1001 I Street
Sacramento, California 95814
Mailing Address: P.O. Box 4010
Sacramento, California 95812-4010
Fax No.: (916) 323-8803
Telephone: (916) 445-6900
Follow this link to download
a copy of this notice.
Follow this link to download
the document providing the basis of determination
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For questions regarding Proposition 65, please contact the Cynthia
Oshita in the Proposition 65 Implementation Program
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